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PART D– Post workshop activity Q1. What is the name of this disease? Describe some of the symptoms and brain pathologies. The name of the disease is Kuru. Kuru is an incurable and life-threatening disease that is witnessed in tribal population of Papua New Guinea. It is a type of spongiform encephalopathy that is highly contagious and could be easily transmitted from one individual to another. Kuru is a degenerative neurological disorder that is caused by prions originating in humans. The word is derived from the word “kuria," which indicates shaking. Kuru is featured by tremors in the body. Body tremors are classical symptoms of the disease. Kuru develops from funerary cannibalism. The disease is commonly witnessed in the “Fore tribe” of Papua New Guinea. The different symptoms of the disease are truncal ataxia, which is featured by headaches, pains in the joint and trembling in limbs. The incubation period is usually 5 to 20 years. The initial symptoms are unstable gait, dysarthria and muscle tremors. As the disease proceeds, the patient has difficulty in walking and suffers from ataxia. The individual suffers from depressive disorders and uncontrolled laughter. In the final stage, the patient suffers from dysphagia and severe ataxia. The disease originates from prions and is strongly related to Creutzfeldt-Jacob disease (CJD). Q2. What is the causative agent of this disease? Why is no immune response observed in patient’s suffering this disease? The disease originates from prions in human beings, and the disease is strongly related to Creutzfeldt-Jacob disease (CJD). Studies have indicated that an individual fails to develop sufficient immunity
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