Physiological changes in patients Don Diabetes Mellitus Type 2
Knowing about Diabetes Mellitus type 2 is to immerse yourself in the field of health is to understand from its beginning how it acts and which those physiological changes that alter the body in equilibrium, in the same way in how a society advances through the time of the time of the same way she has passed by giving her first appearance in a papyrus found by German George and. In 1873 in Luxar that contained health issues and among them this disease.
It is a very serious disease that has a lot of significance that suffers from it constituting a real problem in the well-being of the person, diagnosing an average 85-95% of people with DM, which in a 2030 the rate of affectation could increase in the population of up to 438 million, which is why the issue to be addressed is very important.
Non -insulin -dependent diabetes is a metabolic disorder that is linked to other parts of the organism both cardiovascular and skin damage.
Diabetes is an alteration of chronic metabolism, it has its beginnings when the pancreas organ does not essentially develop insulin or can also be due when the organism itself does not correctly effect the insulin it generates.
Diabetes mellitus 2 occurs because the organism is unable to use insulin correctly arising as an excess of overweight or sedentary lifestyle, it is that alteration of the organism where the level of blood sugar is in excess excess excess.
This DM2 is related to excess weight, sedentary lifestyle, and inappropriate diet, this disease has much more relevance in people who already have an antecedent as high blood pressure, as well as obesity also by family history.
Clinical manifestations in people suffering from this type 2 diabetes mellitus disease are sometimes present. Among them are excess urine, increased thirst, a lot of hunger, a very low weight. On other occasions they can present joint pain and even have good vision.
Pathophysiology
The main event that leads to the appearance of diabetes mellitus is the decrease in insulin caused by incorrect functioning or descent of the beta cells of the pancreas involving other organs as a central and kidney nervous system.
The pathophysiology of type 2 diabetes mellitus is associated with the patient’s obesity status and therefore with insulin resistance causing alterations in the beta cells of the pancreas. Patients with type 2 diabetes mellitus are associated with insulin descent accompanied with losses of cell mass by glycos.
To overcome the Beta cells of the pancreas, they carry out a process that leads to the increase in cell mass to compensate for insulin resistance allowing glucose to return to its normal state. Over time the beta cells of the pancreas are decrease losing the ease of producing and maintaining hyperinsulinemia thus giving an insulin deficit.
DM2’s pathophysiology is associated with important stages:
- Insulin resistance in peripheral tissues and an abnormal insulin increase where a normal equilibrium state is no longer achieved.
- Decrease in the correct function of the beta cells of the pancreas ceasing the synthesis of hormones appearing type 2 diabetes
Treatment
In the treatment of diabetes mellitus 2 they include a wide variety of alternatives to be carried out both in the diet, exercises, as well as the apply of oral drugs and insulin where the patient will have to be prepared with the indications that the personnel Health will make him known in his process.
Non -pharmacological treatment
- The patient’s healthy lifestyle change is very important for the control of the disease and also reduces the incidence of complications, there are multidisciplinary teams that help the patient in this disease process.
- Diabetological education: it is an important point as a treatment since it allows the decrease in diabetic commas, amputations in addition to being in a hospital in a hospital, this treatment can be carried out independently or collectively.
- Diet: It is very important in the control of your diet this must be balanced.
- Health research has announced that individuals who carry out physical activities minimize the degree of diabetes appearance It is therefore that increasing physical exercises in patients with diabetes such as moderate aerobics is an effective method in treatment since it reduces basal and postprandial blood glucose , helping weight loss.
Pharmacotherapy
- For both patients with excess weight or as not, the metformin minimizes 1 to 2 % HBA1C.
- Oral antibiotics: drugs are administered thirty minutes before each meal.
- Sensitizers, secretagogues, inhibitors of the alpha glycosidase, GLP 1 agonists, DPP IV inhibitors.
- Tiazolidinedionas, insulin -release pills, starch blockers, amiline analogues.
- Insulin produced by Langerhans islets are indicated in the patient with a clinical picture of severe insulinopenia this is that medication that has had great impact on the person’s health status is a single antidiabetic drug that contains hypoglycemic allowing to control the values of HBA becoming an inescapable medication.
Conclusions
The origin of Diabetes Mellitus Types 2 has many ranges that have not yet been very specific to ignore their cause between 70 and 85% in the people who suffer, taking as a factor the genetic base and in other aspects the overweight, high voltage arterial, as well as family history, food with carbohydrates, hormones, and an inactive lifestyle.
The physiological events that conveys a loss of beta cells of the pancreas in diabetes mellitus type 2.
The main cause of the appearance of type 2 diabetes mellitus is determined by several components in which it has a lot to do with the food habit of the person and its genetic base, it can occur at any age, although it is in greater incidence in people Middle or higher age, this arises as a result of excess blood sugar when the body does not perform or does not use insulin in a correct way arising an excess storage of sugar in the circulatory system and causing a deficit in the nourishment of cells. As for its treatment, it is in two alternatives a preventive one with drugs such as metformin, career, rephakmid, roziglitazone and another treatment that does not use drugs is integral and depends on the healthy lifestyle that the person carries.
Leave feedback