DLBCLMost common form of Non-Hodgkin’s lymphoma.

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DLBCLMost common form of Non-Hodgkin’s lymphoma. It is a cancer of the B-lymphocytes. Accounts for 49% cases of Non-Hodgkin’s lymphoma (Gouveia, Siqueira, & Pereira, 2012).Case StudyPatient presented with DLBCL in the mediastinum and was at-risk of developing cardiovascular collapse. Pathophysiology Multiple lesions in molecular pathways of B-lymphocyte differentiation and proliferation activates oncogenes. Increased expression of BCL2, BCL6 and MYC) Inactivation of tumor suppressor genes like p53 and INK4 (Akyurek et al,

Free DLBCLMost common form of Non-Hodgkin’s lymphoma. Essay Sample

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