Physical and mental disorders related to LSD consumption
LSD are the acronym in English of lysergic acid diethylamide. This is an illegal drug that occurs in white dust or a light liquid without color. It is available in dust, liquid, tablet or capsule. The LSD is normally ingested orally. Some people inhale by the nose (aspirated) or inject it into a vein (fired).
The street names of the LSD include acid, drying paper, drying acid, blue joy, kool-aid electric, bumps, lucy in the sky with diamonds, soft yellow, microputs, purple mist, sugar lumps, sun eyelashes, and glass of the glasswindow.
Discovery of the LSD
On November 16, 1938, the Swiss chemist Albert Hofmann synthesized for the first time the LSD (lysergic acid diethylamid) in the Sandoz de Basel laboratories (Switzerland), during a research program that sought the possible uses of the Ergolina group alkaloids, present in the Cornezuelo del Centeno. Hoffman discovered the high psychotropic power of LSD by accidentally ingesting it
Where does it come from?
The Cornez of the Centeno (Claviceps Purpurea) is a parasite fungus of the genus Claviceps consisting of more than fifty species. All of them can affect a wide variety of cereals and herbs, although their most common host is rye. When the corn core is deposited on Earth, it remains in a lethargic state or sclerotium until the conducive conditions are given to measure and move on to the fruitful phase, in which it develops as a tiny mushroom by releasing the fungal spores. These spores are very elongated with a thickness of just 1 micra. The infestations of this fungus cause the reduction of production in quality and quantity of grain and hay and, if these infected crops are used to feed cattle, they can cause a disease called ergotism.
Effects
The first effects of the LSD appear between 30 and 90 minutes after administration. They can last from 7 to 12 hours, and reaches their maximum power between 3 and 5 hours.
Its most significant effects are psychological and are known as a travel name. However, they depend largely on the amount ingested. According to the doses administered, the effects can vary from small distortions of perception – mainly visual and auditory – to hallucinations and disconnection of reality.
When the LSD produces unpleasant experiences, there is talk of "bad trip". This is the most remarkable risk of its ingestion and hallucinogenic drugs in general. You can experience a loss of emotional control, anxiety or panic.
LSD can also cause serious psychiatric alterations, such as anxiety and psychosis pictures. In general, it is rare for these sensations to extend beyond the duration of their effects. However, in people with predisposition to suffer some kind of psychological or psychiatric disorder, it can trigger temporarily disorder – repeating over time (anxiety disorder) – or chronic (schizophrenia). Hence it is especially contraindicated in these people. Great anxiety..
Short -term effects of the LSD
This drug significantly stimulates serotonin levels, hormone responsible for regulating emotions, appetite, sleep and sensitivity. Its effects take between 20 and 40 minutes to appear, dilating the pupils, increasing body temperature, heart rate and blood pressure.
The LSD is consumed orally through sugar, sweets, gummies, gelatin or small drying paper paintings. This is a spongy role that is used to absorb excess liquid substances, which are distinguished by their different prints. All of them bathed in a small dose of LSD liquid.
This liquid can also be administered by injected into the body’s muscles. Its effects last from six to twelve hours, depending on the size of the dose, the frequency of consumption, the weight or age of the consumer, all this affects.
Long -term effects of the LSD
Delirium episodes are presented that in some cases are accompanied by aggressiveness, many people have tried to kill someone, take their lives themselves or sometimes they have led them to madness, staying on that trip through the strong hallucinations that occur.
Without forgetting that a negative effect of the consumption of the very recurring LSD in the long term is the "flash-back", this is an experience caused by the effects of hallucinogenic drug after days, weeks, months and even years of having consumed it.
This effect can be caused by the use of any drugs, episodes of stress, fatigue or physical exercise, which can cause a feeling of pleasure, satisfaction or cause great anxiety.
The LSD triggers a reduction in communication between brain regions that are responsible for the psychological balance necessary for planning and decision -making. At the same time, the LSD increases connectivity in brain networks associated with sensory functions and movement. Based on brain signal patterns, scientists could also establish that changes in brain connectivity caused by LSD are linked to a particular receiver in the brain (serotonin-2a receptor) 2A)
Treatment for psychosis
On the other hand, disorders in sensory perception and thought, triggered by LSD, are similar to changes in perception and thinking that appear in patients with psychotic disorders such as schizophrenia.
‘The new findings can also have an immediate impact on the treatment of psychotic symptoms, as in schizophrenia, for example,’ adds Franz Vollenweider, another of the researchers.
Most patients with schizophrenia are treated with antipsychotic drugs, which block some of the serotonin receptors identified by the new study. However, there are many patients who do not respond to this treatment.
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